Publications
Vorselen, D.*, Kamber, R.A.*, Labitigan, R.L.D., van Loon, A.P., Peterman, E., Delgado, M.K., Lin, S., Rasmussen, J.P., Bassik, M.C.#, Theriot, J.A.#
Cell surface receptors TREM2, CD14 and integrin αMβ2 drive sinking engulfment in phosphatidylserine-mediated phagocytosis.bioRxiv
Akdoğan, E., Lundgren, S.M., Kamber, R.A., Bassik, M.C., Collins, S.R.
Parallel CRISPR screens reveal pathways controlling the cell surface levels of the attractant receptor FPR1.Communications Biology, 2026
Tycko, J., Van, M., Aradhana, DelRosso, N., Ye, H., Yao, D., Valbuena, R., Vaughan-Jackson, A., Xu, X., Ludwig, C., Spees, K., Liu, K., Gu, M., Khare, V., Mukund, A.X., Suzuki, P.H., Arana, S., Zhang, C., Du, P.P., Ornstein, T.S., Hess, G.T., Kamber, R.A., Qi, L.S., Khalil, A.S., Bintu, L., Bassik, M.C.
Development of compact transcriptional effectors using high-throughput measurements in diverse contexts.Nature Biotechnology, 43(9), 1525-1538, 2025
Liu, S.J., Zou, C., Pak, J., Morse, A., Pang, D., Casey-Clyde, T., Borah, A.A., Wu, D., Seo, K., O'Loughlin, T., Lim, D.A., Ozawa, T., Berger, M., Kamber, R.A., Weiss, W.A., Raleigh, D.R.#, Gilbert, L.A.#
In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma.Genome Biology, 25(1), 256, 2024
Amaya, L., Abe, B., Liu, J., Zhao, F., Zhang, W.L., Chen, R., Li, R., Wang, S., Kamber, R.A., Tsai, M.C., Bassik, M.C., Majeti, R., Chang, H.
Pathways for macrophage uptake of cell-free circular RNAs.Molecular Cell, 84(11), 2024
Ahn, G., Riley, N., Kamber, R.A., Wisnovsky, S., Moncayo von Hase, S., Bassik, M.C., Banik, S.M., Bertozzi, C.R.
Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras.Science, 382(6668), 2023
Chen, Y., Craven, G.B., Kamber, R.A., Cuesta, A., Zhersh, S., Moroz, Y.S., Bassik, M.C., Taunton, J.
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes.Nature Chemistry, pp.1-10, 2023
Yu, H.*, Kamber, R.A.*, Denic, V.
The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor to suppress pexophagy in yeast.eLife, 11, e74531, 2022
Kamber, R.A., Nishiga, Y., Morton, B., Banuelos, A.M., Barkal, A.M., Vences-Catalan, F., Gu, M., Fernandez, D., Seoane, J.A., Yao, D., Liu, K., Lin, S., Spees, K., Curtis, C., Jerby-Arnon, L., Weissman, I.L., Sage, J., Bassik, M.C.
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis.Nature, 597(7877), 549-554, 2021
Wainberg, M.*, Kamber, R.A.*, Balsubramani, A.*, Meyers, R.M., Sinnott-Armstrong, N., Hornburg, D., Jiang, L., Chan, J., Jian, R., Gu, M., Shcherbina, A., Dubreuil, M.M., Meuleman, W., Spees, K., Snyder, M.P., Bassik, M.C.#, Kundaje, A.#
A genome-wide atlas of co-essential modules assigns function to uncharacterized genes.Nature Genetics, 53(5), 638-649, 2021
Han, K., Pierce, S.E., Li, A., Spees, K., Anderson, G.R., Seoane, J.A., Lo, Y.H., Dubreuil, M., Olivas, M., Kamber, R.A., Wainberg, M., Kostyrko, K., Kelly, M.R., Yousefi, M., Simpkins, S.W., Yao, D., Lee, K., Kuo, C.J., Jackson, P.K., Sweet-Cordero, A., Kundaje, A., Gentles, A.J., Curtis, C., Winslow, M.M., Bassik, M.C.
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.Nature, 580(7801), 136-141, 2020
Haney, M.*, Bohlen, C.*#, Morgens, D., Ousey, J., Barkal, A., Tsui, K., Ego, B., Levin, R., Kamber, R.A., Collins, H., Tucker, A., Li, A., Vorselen, D., Labitagan, L., Crane, E., Boyle, E., Jiang, L., Chan, J., Rincon, E., Greenleaf, W., Li, B., Snyder, M., Weissman, I., Theriot, J., Collins, S., Barres, B., Bassik, M.#
Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.Nature Genetics, 50(12), 1716-1729, 2018
Weir, N.R., Kamber, R.A., Martenson, J.S., Denic, V.
The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane.eLife, 6, e28507, 2017
Eapen, V.V., Waterman, D.P., Bernard, A., Schiffman, N., Sayas, E., Kamber, R.A., Lemos, B., Memisoglu, G., Ang, J., Mazella, A., Chuartzman, S.G., Loewith, R., Schuldiner, M., Denic, V., Klionsky, D.J., Haber, J.
A novel pathway of targeted autophagy is induced by DNA damage in budding yeast.PNAS, 114(7), E1158-E1167, 2017
Kamber, R.A.*, Shoemaker, C.J.*, Denic, V.
Receptor-bound targets of selective autophagy use a scaffold protein to activate the Atg1 kinase.Molecular Cell, 59(3), 372-381, 2015
Kamber, R.A.*, Shoemaker, C.J.*, Denic, V.
A molecular switch for selective autophagosome formation.Autophagy, 11(11), 2132-2133 (Perspective), 2015
Valenzano, D.R., Kirschner, J., Kamber, R.A., Zhang, E., Weber, D., Cellerino, A., Englert, C., Platzer, M., Reichwald, K., Brunet, A.
Mapping loci associated with tail color and sex determination in the short-lived fish Nothobranchius furzeri.Genetics, 183(4), 1385-1395, 2009
*Equal contribution | #Co-corresponding authors | Kamber Lab authors in bold